Uitspraak van verwijderd op vrijdag 4 september 2009 om 18:59:
Shuglin vindt dat er veel overeenkomsten zijn tussen de 2, de verschillen zijn vooral fysiek. Bij T2 is een grotere kans is op fysieke klachten(misselijkheid of diarree). Met T7 is er minder kans op klachten maar de effecten duren bijna 2 keer zo lang. Beide zijn vaak gebruikt in therapie na MDMA.
Klopt, dat is dan vooral wat alleen Shulgin er van vindt. Grotere groepen zijn het daar toch niet helemaal mee eens; met name lijkt het erop dat er juist minder klachten zijn op T2 dan op T7, maar diverse meningen blijven verschillen. Uit eigen ervaring vind ik T7 echt max 1,5x langer duren en
zeker niet 2x langer dan T2.
Heb twee aardige artikelen die
T2 vs. T7 benaderen, de bovenste die ik ga quoten heb ik al eens helemaal gelezen en is interessant, de onderste heb ik net gevonden toen ik het bovenste artikel trachtte op te zoeken:
Artikel 1: valt te lezen op:
http://www.drugs-forum.com/forum/showthread.php?t=780
en bestaat uit meerdere delen, onder andere:
User Quotes 2C-T-2 vs. 2C-T-7
by Murple, Feb 6, 2001
<DT>I found 2C-T-2 to be nothing at all like 2C-T-7. It has an all together different nature. ... 2C-T-2 hits you hard and fast. 2C-T-7 has a long and slow come up, yet they both peak by the three-hour point. ... 2C-T-2 is not a very visual psychedelic. I had very nice visuals, don't get me wrong, but NOTHING at all like I would on 2C-T-7. ... I was very nauseous in the beginning [of the 2C-T-2 trip], more so than with 2C-T-7 ... It is definitely stronger on a milligram per milligram basis compared to 2C-T-7, as 20 mg of 2C-T-7 would not have been that strong. 2C-T-2 seemed to do little to the music. Again, this is not 2C-T-7. To me, it was more of an introspective head-trip, rather than the mind candy effects of 2C-T-7. I was lost in internal thought, rather than becoming enthralled with the outside world. I disagree with an Internet posting that stated 2C-T-2 is a wannabe 2C-T-7. ... I never experienced any of the body-load that 2C-T-2 has been accused of producing. In fact, it much easier on my body than 2C-T-7 ever has been. ... If you want mind-blowing visuals like those produced by 2C-T-7, this is not your drug. But for an introspective journey with a somewhat short duration and a non-threatening nature, this is the chemical for you. Morning glory seed</DT>
<DT>The visual aspect [of 2C-T-7] was nice, but less pronounced than the visuals from 2C-T-2 or mescaline. The physical body high was similar to mescaline, and quite enjoyable... except towards the end I felt some uncomfortable neck and shoulder muscle tension similar to the phenomenon one of Shulgins associates in PiHKAL described as the 'MDA cloak'. During the peak, I noticed extreme time dilation, similar to 2C-T-2. I also noticed some very extreme aphrodisiac effects during the first hour or so of the trip. This material also doesn't seem to kill the appetite, and I found making and eating a meal after the peak to be an incredible experience. From the time I ate the drug until I was able to fall asleep was around 9 hours. I found the trip to be comparable to 20mg of 2C-T-2, although there are very significant differences between the two. ... Its interesting that I'm unusually sensitive to 2C-T-7, though I show no unusual sensitivity to 2C-T-2. Just goes to show that you cant make assumptions one one drug based on another, no matter how similar they may be.
<DD>-Murple
<DT>Kind of similar to T-7, more distortion, less warmth. With T-7 there is a gentle contentment that is not present here. This is more like the apathy of LSD. The visuals are not the smooth waves of color I get from T-7, but more a fragmentation and 3-dimensional layering with similar refraction.There is no nausea as with T-7 liftoff.
<DD>-Ouro
<DT>It seemed to me, after later getting a chance to try2ct7, that 2ct2 was a 'wannabe' version of 2ct7, only without quite as much good clean fun buried within it, and for me at least, a significantly higher body load. Scotto</DT>
Artikel 2:
http://www.erowid.org/chemicals/2ct7/article1/survey.shtml
o.a.:
The typical doses used by those taking 2C-T-2 orally ranged from 5mg to 40mg, with the average being 20.76mg. For those who snort the drug, the typical doses ranged from 2.5mg to 35mg, with the average being 13.07mg.
For 2C-T-7, the typical oral doses ranged from 1mg to 125mg, with the average being 26.64mg.
This paper has been a fascinating project, and I hope that it will help to characterize two very interesting molecules. However, like almost all research, I feel that it has raised more questions than it has answered. Early 2000, when this project was first conceived, 2C-T-2 and 2C-T-7 were obscure and vaguely defined psychedelics. Today, they remain relatively obscure, but their personalities have been manifested to a much greater degree.
Until recently, 2C-T-2 and 2C-T-7 were seen by many as being mere substitutes for 2C-B or mescaline, having no real uniquenesses of their own. This belief may go a long way toward explaining why neither 2C-T-2 nor 2C-T-7 have been the subject of much scientific investigation.
Furthermore, the identities of both drugs have long been blurred. An interesting lesson in the power of speaking first may be found in this story.
Writing in PIHKAL, Alexander Shulgin states "There is a considerable parallel between 2C-T-2 and 2C-T-7, and both have proven to be excellent tools for introspection. The differences are largely physical. With 2C-T-2, there is more of a tendency to have physical disturbances such as nausea and diarrhea. And the experience is distinctly shorter. With 2C-T-7, physical disturbances are less common, but you are into the effects for almost twice as long."Based on this one paragraph, many people have concluded that 2C-T-2 is simply a shorter and inferior version of 2C-T-7. It has to be remembered that every person responds differently to every drug, and that Shulgin's statement is true only for himself and for people he has observed using the drugs. By virtue of being the first person to write about these two drugs however, his opinion has been taken by many as gospel. As more people have used these drugs,
it has become clear that Shulgin's results are not universal. For many people, 2C-T-2 is the superior drug. The results of my user surveys ironically show a higher incidence of physical discomfort among 2C-T-7 users. It also has become clear that the two differ not only in side effects but also in primary effects. Most people who have tried both find that they have significant differences in the states of mind they can produce as well as significant differences in the quality and quantity of visual effects.
The two are clearly different drugs with different effects profiles.[/quote]
En nog een frapante en belangrijke:
As an added testimony to the power of suggestion, I was amused when I spoke with several people who thought they had tried both 2C-T-2 and 2C-T-7. Each of these people was emphatic about having had much better experiences with 2C-T-7 than with 2C-T-2. All insisted that 2C-T-7 was much gentler on the body. Upon further questioning, it turned out that they had obtained both drugs in the Netherlands, and that the 2C-T-7 they had tried was in fact the mislabelled 2C-T-2.
As Shulgin describes in PIHKAL, new drugs come into the world as blank slates. With each time it is taken by a human, its personality is manifested more and more. Over time, we can form a fairly clear image of a drug's nature, though as with a person, we can never really know everything there is to know. Both 2C-T-2 and 2C-T-7 have grown up rapidly in the past four years. It seems clear that both are fairly typical members of the phenethylamine family, with much in common with Mother Mescaline and their older sibling 2C-B. Each has their own personality, however. Both also remain children, and there remains much to learn.
Several areas seem worthy of further study by those who are better equipped than I for scientific research. First, toxicological studies need to be carried out to determine what the risk factors are. This goes especially for 2C-T-7, which has been linked to some worrisome incidents. It is crucial that we determine whether the death of Jake Duroy and the other reported incidents were due to some unknown pharmacological actions, were overdoses, or were simply freak accidents. Hand in hand with this, experiments to determine the receptor affinities of each drug as well as their metabolic pathways may provide useful information. The unusual reaction to 2C-T-7 described in the pharmacology section by the man taking beta-blocker medications seems particularly interesting, considering that mescaline is suspected of competing for alpha-adrenergic receptors but appears not to interact with beta-adrenergic receptors. Investigating the receptor affinities of 2C-T-2 and 2C-T-7 may shed some light on unanswered questions about mescaline's pharmacology. As for metabolic pathways, I suspect it would be worthwhile to try and compare the metabolism of 2C-T-2 versus 2C-T-7. When comparing reports from users, 2C-T-7 produces dramatically variable responses in different people, with some people having strong trips at 10mg and others barely feeling 50mg. With 2C-T-2, dosages seem to be much more consistent from person to person. This different response has been reported even by people who have tried both drugs. It seems possible that some difference in the way each drug is metabolized could be responsible for this phenomenon.
Another direction worthy of further research, one which I may pursue myself in the near future, would be more user surveys. First, it would be nice to get more data on 2C-T-2 versus 2C-T-7, asking similar questions to those asked on the survey I conducted for this paper. Nearly ten times the number of 2C-T-7 surveys were received, making direct comparison somewhat difficult. This was rather disappointing, as I expected much more response on 2C-T-2 owing to its popularity in Europe a few years ago. Beyond this, I feel it would be productive to try to gather data on more subjective points. Some questions which seem appropriate would include questions on the duration of the experience, the intensity levels of various effects such as visuals, euphoria, panic, and insights or revelations. Again, I feel it important to try to compare 2C-T-2 and 2C-T-7. Casual analysis of published first hand reports seems to indicate that the two drugs produce substantially different subjective effects, and trying to quantify these differences would help to establish what strengths and weaknesses each drug may have as potential tools for psychotherapy, creativity enhancement, or spiritual practices.
Both 2C-T-2 and 2C-T-7 are drugs which I feel have significant potential. As tools for therapy, both seem to promote very insightful states of mind, and allow the well-intentioned user to step outside of emotional entanglements and review their lives objectively, acceptingly, and compassionately. Others report emotional opening and release, and increased empathy with people. Many reports describe long lasting feelings of optimism, happiness, and personal growth following experiences with either drug. Both drugs also hold great promise as spiritual tools, enabling easier access to meditative states. In particular, 2C-T-7 seems to be associated with a very centered state, and the increased body awareness and flexibility it produces seems very conducive to practices such as yoga and tai chi. Both drugs have been reported by users as opening the heart chakra. As with most psychedelics, there seems great potential for the use of both drugs as sources of creative inspiration.
Along with the potential for benefit, both drugs also present potential risks. This seems especially true for 2C-T-7, although this could be a distortion of the facts caused by a much smaller sample size of 2C-T-2 users responding to the surveys, or a reflection of the fact that many 2C-T-2 users seem to be more cautious and educated than many 2C-T-7 users. While there have been no significant incidents reported involving 2C-T-2, it is better to be too cautious than not cautious enough. Used in moderation, both drugs seem to be quite safe. While there have been several serious incidents reported, we need to remember that this represents only a tiny fraction of total uses. There have been fewer than ten incidents of concern, out of thousands of total uses. This record looks even better when considering some of the reckless dosages taken by many people.
The biggest risk of course is that the risk factors are not really known. Until more research is done, it would be wise to proceed carefully. People taking 2C-T-2 or 2C-T-7 should avoid mixing them with other drugs; if someone does decide to try a drug combination, it would be a good idea to start with a lower than normal dose. People with potentially life threatening medical conditions should avoid taking 2C-T-2 or 2C-T-7, or at least start with very low doses.
The most common cause of bad reactions to any drug is taking too much. This definitely applies to both 2C-T-2 and 2C-T-7. Many users are careless about dosage measurement, using ineffective techniques such as the graph paper method or even just guessing. Large doses of either drug, but particularly 2C-T-7, can lead to states of extreme confusion and detatchment from physical reality. This can lead to panic reactions, toxic psychosis, and physical injuries due to being unaware of one's surroundings. It is even possible that with a large enough dose, death due to overdose toxicity could occur. In my opinion, many people who are taking such large doses are missing the point of these drugs. People taking extremely large doses often mention that they are seeking powerful visual effects. While 2C-T-2 and 2C-T-7 can both be extremely visual drugs, I don't feel that these are the primary focus of the experience. I feel that the primary strength of these drugs lies in their effects on the thought processes and emotions, subtle effects which are optimally experienced in lower dosages than are required for the overpowering visuals. I believe that the state many of the visual seekers are trying to achieve are in fact mild overdoses, as physical discomfort can become quite pronounced at such dosage levels. While I firmly believe in the right of these people to take such doses if that makes them happy, they may wish to consider turning to drugs such as DMT which produce intense visuals in more reasonable dosages, with much less physical side effects. First time users of either drug should limit their doses to 10 to 15mg orally.
One other suggestion for minimizing bad reactions is to take these drugs orally. Other routes carry much higher risk of accidentally taking too much, due to the much smaller dosage ranges involved. Although a very popular method, snorting these drugs dramatically increases the variety, intensity, and duration of side effects. Of all the bad reactions which have been reported, whether physical or psychological, the overwhelming majority involved cases where the drug was insufflated. In addition to the much smaller dose ranges involved, the rapid onset of effects can take many people by surprise. Rather than a serene and gradual two hour ramp up when taken orally, snorting it can result in a very sudden and rapid catapulting into an extremely altered state of mind. Oral doses offer fewer side effects, a wider margin of error in dose measurement, and a gentler transition into the experience. In addition, there is none of the intense pain nor the potential for damage to the nasal passeges which are present when snorting them. I strongly discourage taking either 2C-T-2 or 2C-T-7 by any route other than by mouth.
I feel one of the most important things people need to realize about both drugs is that they are still experimental drugs. In the end, it is very likely that research will show them both to be very safe and useful drugs - but until that research has been done, it is important to be respectful of the experimental nature of 2C-T-2 and 2C-T-7. It is also possible that research will show them to be dangerous drugs which work very differently from mescaline. Anyone considering using them should keep this in mind and not use the drugs recklessly. Use low doses, and take long breaks between uses of either drug. You can always take a higher dose next time, but you can't go back and untake some if you take too much and have a bad reaction. Avoid putting these chemicals in the hands of people who you do not honestly believe can use them responsibly.I firmly believe that people have the right to be irresponsible and self-destructive, but at the same time I also believe that those of us who know better should not go out of our ways to help them. The right to be stupid can not and must not be hindered if we are to live in a free and civilized society. That doesn't mean it should be encouraged, however.
Chemistry has given us two very interesting chemicals in 2C-T-2 and 2C-T-7. Both hold great promise as tools to benefit mankind. Let's learn what we can about them, and perhaps then we may learn from them.
En meer cijfermatig:
Both drugs produced a range of physical side effects. Out of all the 2C-T-2 users, 8 (18.60% ) reported the side effects were barely noticable. 11 (25.58% ) found them to be mild and of short duration. 10 (23.26% ) found them short but distracting, and 5 (11.63% ) found them to be short but severe. 3 users (6.98% ) found the side effects lasted a long time but were mild. 5 (11.63% ) found them long and distracting. 1 person (2.33% ) did not respond to this question. When looking only at users who take the drug orally, 4 (11.11% ) found the side effects were barely noticable. 10 (27.78% ) found that the side effects were short and mild, 9 (25.00% ) found them to be short but distracting, 5 (13.89% ) found them short and severe, 3 (8.33% ) reported mild but long lasting side effects, and 4 (11.11% ) found them long and distracting. 1 of the oral users (2.78% ) did not respond. Of the insufflators, 4 (57.14% ) found the side effects barely noticable. 1 person (14.29% ) found them short and mild, 1 (14.29% ) found them short and distracting, and 1 (14.29% ) found them long and distracting. I suspect these figures may be highly unreliable, as the sample size of people who snort 2C-T-2 is only 7 individuals. Given a larger sample size I believe that the side effects would be more pronounced for insufflation than for oral use, as is the case with 2C-T-7.
Out of all the 2C-T-7 users, 62 (14.66% ) found the side effects to be barely noticable. 121 (28.61% ) found the side effects to be short and mild. 105 (24.82% ) found them to be short and distracting. 34 (8.04% ) found the side effects to be short but severe. 53 respondents (12.53% ) found the side effects mild but long lasting. 29 (6.86% ) found them to be long and distracting. 8 (2.60% ) found the side effects to be long lasting and severe. 11 people (2.60% ) did not indicate the level of side effects intensity. When comparing different routes of consumption, there are some rather big differences. Oral administration seems to have the mildest level of side effects, with 49 people (17.01% ) reporting them as barely noticable. 87 respondents (30.21% ) reported the side effects as short and mild. 66 (22.92% ) said the side effects were distracting but short, and 18 (6.25% ) said they were short but severe. 33 people (11.46% ) said the side effects were long and mild, 20 (6.94% ) said they were long and distracting, and 6 (2.08% ) found them long and severe. 9 (3.13% ) of the oral users did not rate the intensity of side effects. People who snort 2C-T-7 had a significantly worse time. 12 (10.17% ) found them to be barely noticable. 28 (23.73% ) found the side effects short but mild. 33 (27.97% ) found them to be short and distracting, and 15 (12.71% ) found them to be short and severe. 17 people (14.41% ) found the side effects to be long but mild, 9 (7.63% ) found them long and distracting, and 2 (1.69% ) found them to be long and severe. 2 (1.69% ) of the insufflators did not answer this question. Of the rectal users, 2 (40% ) found the side effects to be short and mild, 2 (40% ) found them short and distracting, and 1 (20% ) found them long and mild. Of those who smoke 2C-T-7, 1 (8.33% ) said the side effects were barely noticable. 4 (33.33% )found them short and mild, 4 (33.33% ) said they were short and distracting, 1 (8.33% ) said the side effects were short but severe, and 2 (16.67% ) found them long but mild.
Nausea was the most common side effect of 2C-T-2, being reported by 26 (60.47%) of all users. Broken down by route, 23 (63.89% ) of oral users and 3 (42.86% ) of insufflating users reported nausea. Nausea was also the most common side effect for 2C-T-7, with 265 (62.65% ) of all users reporting it. Broken down by route, 180 (62.50% ) of oral users, 76 (64.41% ) of insufflating users, 3 (60% ) of rectal users and 6 (50% ) of smokers experienced nausea.
Maakt elkaar dus niet veel, 2%.
Vomiting was reported by 10 (23.26% ) of all 2C-T-2 users. By route, 8 (22.22% ) of the oral and 2 (28.57% ) of the insufflating users reported that they threw up. 2C-T-7 gave somewhat worse results, with 129 (30.50% ) of all users vomiting. By route, oral users fared much better, with 77 (26.74% ) throwing up, compared to 45 (38.14% ) of insufflating users, 2 (40% ) of rectal users, and 5 (41.67% ) of the smokers.
Dit maakt dus wel wat uit, ten nadele van T7. In onze groep is het 0 bij T2, 2 bij T7.
For both drugs, muscle tension was the second most common side effect. Of all 2C-T-2 users, 14 (32.56% ) experienced it. By route, 12 (33.33% ) of oral users and 2 (28.57% ) of insufflating users reported muscle tension. Again, 2C-T-7 gave noticably worse results, with 197 (46.57% ) of all users reporting muscle tension. By route, 141 (48.96% ) of oral users, 47 (39.83% ) of insufflating users, 3 (60% ) of rectal users, and 6 (50% ) of smokers reported muscle tension. Many people pointed out that this muscle tension was focused in the neck and shoulders. A few people indicated it occurred primarily during the early part of the trip.
Scheelt dus een 14%, ten nadele van T7.
Out of all 2C-T-2 users, 8 (18.60% ) reported diarrhea. Of the oral users, 7 (19.44% ) reported diarrhea, as did 1 (14.29% ) of the insufflating users. For 2C-T-7 users this seemed to be less common, with only 26 (6.15% ) of all users reporting diarrhea. By route, 18 (6.25% ) of oral users, 5 (4.24% ) of insufflating users, and 3 (25% ) of 2C-T-7 smokers reported diarrhea.
Diarree dus wel vaker bij T2 dan bij T7.
Tachycardia was reported by 7 (16.28% ) of all 2C-T-2 users - all of whom had taken it orally, making the percentage of oral users reporting it 19.44%. For 2C-T-7, 92 (21.75% ) of all users experienced tachycardia. Broken down by route, 60 (20.83% ) of oral users, 29 (24.57% ) of insufflating users, and 3 (25%) of smokers reported tachycardia.
Meer gevallen van een opgemerkte (en hinderlijke?!) snelle hartslag (100+BPM) bij T7 dus.
Hypertension was reported by 1 2C-T-2 user, who took it orally, making the percentage of all users experiencing this effect 2.33%, or 2.78% of oral users. Again, 2C-T-7 did somewhat worse, with 25 (5.91% ) of all 2C-T-7 users reporting hypertension. By route, 16 (5.55% ) of oral users, 8 (6.78% ) of insufflating users, and 1 (8.33% ) of smokers reporting it.
Dehydration was reported by 7 (16.28% ) of 2C-T-2 users. Of those taking it orally, 6 (16.67% ) reported dehydration, as did 1 (14.29% ) of the insufflating users. 2C-T-7 gave similar results, with 76 (17.96% ) of respondents reporting dehydration. By route, 53 (18.40% ) of oral users, 20 (16.95% ) of insufflating users, and 3 (25% ) of smokers reported dehydration.
Hierin lichte nadelige cijfers voor T7.
Headaches were fairly uncommon for 2C-T-2 users, with 4 (9.30% ) users reporting them. These users all took it orally, making the occurrence of headaches with oral use 11.11%. Here, 2C-T-7 gave dramatically worse results. 135 (31.91% ) of 2C-T-7 users reported headaches. By route, 92 (31.94% ) of oral users, 36 (30.51% ) of insufflating users, 2 (40% ) of rectal users, and 5 (41.67% ) of smokers got headaches. Several people commented that the headache seemed to come most often near the end of the experience, and some felt they may be due to dehydration. One person described the headache as "brain-freezesque" feeling. Another said that the headache was accompanied by a very intense buzzing pressure in the sides of his head.
Veel meer hoofdpijn dus bij T7!
Both drugs also caused various other side effects.
Of all 2C-T-2 users, 7 (16.28% ) - all oral users, making up 19.44% of that group - reported other side effects. Side effects reported included a stomach ache, nasal congestion (in someone who took the drug orally), and a tingling pins-and-needles sensation in the extremities. One person reported feeling an unusual sensual arousal without any apparent external cause. One person reported confusion.
With 2C-T-7, 118 (27.90% ) of all users reported other side effects. By route, 72 (25% ) of oral users, 42 (35.59% ) of insufflating users, 1 (20% ) of rectal users and 3 (25% ) of smokers reported miscellaneous side effects.
Dus ook meer van de niet hierboven genoemde side effecten bij T7 dan bij T2.
Artikel 1 heeft een dergelijke strekking.
Edit, veel

smiley's eruit gehaald

; ipv daarvan zie je veel % )
Als je het zo leest, vind ik het ineens jammer dat de T2 voorraad niet zo groot meer is itt de T7 voorraad die uit aardig wat meer bestaat. Hmm.. en T2 is ook niet meer zo gunstig te verkrijgen hier
