 A-lusion · DJ, producer, live | Ed Sheeran · zang | Mad Dog · DJ, producer, live | Sharon Doorson · zang |
| Ali B · rap | Frontliner · DJ, producer, live | The Nasty Boyz · live | Showtek · DJ, producer, live |
| Alpha² · DJ, producer, live | G-Town Madness · DJ, live | Neophyte · DJ, producer, live | sinaK-E |
| André Hazes · zang | Gerard Joling · zang | Noisecontrollers · DJ, producer, live — | Da Syndrome · MC |
| Angerfist · DJ, producer, live | Gordon · zang | Noize Suppressor · DJ, producer, live | Tatanka · DJ, producer, live |
| Art of Fighters · DJ, live | Headhunterz · DJ, live | O'G3NE · zang | Technoboy · DJ, producer |
| The Beholder · DJ, producer, live | Isaac · DJ, producer | Partyraiser · DJ, producer, live | Tommyknocker · DJ, producer |
| Blademasterz · DJ, producer, live | Jan Smit · MC, zang | Pavo · DJ, producer | The Viper · DJ, producer, live |
| Brennan Heart · DJ, producer, live | K-otic · zang | Project One · DJ, producer, live | Wildstylez · DJ, live |
| D-Block & S-te-Fan · DJ, producer, live | Korsakoff · DJ, live | Promo · DJ, producer, live | Zany · DJ, producer, live |
| D33t | Lil Kleine · rap | The Prophet · DJ, producer, live | Zatox · DJ, producer, live |
| Donkey Rollers · DJ, producer, live | Luna · DJ, producer | Scope DJ · DJ, producer, live | |
@ DefQon.1 2010
